Effects of long term feeding of acetone extract of Momordica charantia (whole fruit powder) on alloxan diabetic albino rats.
نویسندگان
چکیده
Acetone extract of whole fruit powder of Momordica charantia a given orally daily lowered the blood sugar and serum cholesterol levels to normal range after 15 to 30 days in alloxan diabetic rats. The blood sugar once lowered after 30 days treatment did not increase even after 15 days of discontinuation of the treatment.
منابع مشابه
Effects of alcoholic extract of Momordica charantia (Linn.) whole fruit powder on the pancreatic islets of alloxan diabetic albino rats.
Alcoholic extract of whole fruit of Momordica charantia was prepared. Adult healthy albino rats were divided into four groups and received a dose of 6 mg/l00 gm. body weight of alloxan monohydrate. Animals of group I served as diabetic control group. The animals of II, III, and IV groups received 25 mg, 50 mg and 75 mg doses of the extract respectively for different durations. 75 mg dose showed...
متن کاملRegeneration of beta cells in islets of Langerhans of pancreas of alloxan diabetic rats by acetone extract of Momordica charantia (Linn.) (bitter gourd) fruits.
Acetone extract of whole fruit powder of M. charantia (bitter gourd) in doses 25, 50 and 75 mg/100 g body weight lowered the blood glucose from 13.30 to 50% after 8 to 30 days treatment in alloxan diabetic albino rats, confirming antihyperglycemic effect of this plant in diabetic animals and humans. Histological observations with acetone extract showed different phases of recovery of beta cells...
متن کاملIn vivo hypoglycemic effect of methanolic fruit extract of Momordica charantia L.
BACKGROUND Momordica charantia L. is a medicinal plant commonly used in the management of diabetes mellitus. OBJECTIVES We investigated the blood glucose lowering effect of the methanolic fruit extract of the Ugandan variety of M. charantia L. in alloxan-induced diabetic albino rats. METHODS 500g of M. charantia powder were macerated in methanol and the extract administered to two groups of...
متن کاملHypolipidemic and Hepatoprotective Effects of Different Fractions of Methanolic Extract of Momordica Charantia (linn.) in Alloxan Induced Diabetic Rats
The study was undertaken to investigate the hypolipidemic and hepatoprotective effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of methanolic extract of Momordica charantia. The different fractions of extract were administered intraperitoneally as a single dose of 150 mg/kg body weight to alloxan induced diabetic rats and found to reduce blood lipid level (Tota...
متن کاملAntidiabetic and Glycogenesis Effects of Different Fractions of Methanolic Extract of Momordica Charantia (linn.) in Alloxan Induced Diabetic Rats
The study was undertaken to investigate the antihyperglycemic, oral glucose tolerance test (OGTT) and glycogenesis effects of the different fractions (Petroleum ether, ethyl acetate and chloroform) of methanolic extract of Momordica charantia. The different fractions of the extract were administered intraperitoneally as a single dose of 150 mg/kg body weight to alloxan induced as well as glucos...
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ورودعنوان ژورنال:
- Indian journal of physiology and pharmacology
دوره 33 2 شماره
صفحات -
تاریخ انتشار 1989